Nanoparticle based Brucella melitensis vaccine induced oxidative stress acts in synergism to immune response
نویسندگان
چکیده
منابع مشابه
Innocuity and immune response to Brucella melitensis Rev.1 vaccine in camels (Camelus dromedarius).
A field trial was conducted in a camel brucellosis-free herd to evaluate antibody response to the Brucella melitensis Rev.1 vaccine in camels and assess shedding of the vaccine strain in milk. Twenty eight camels were divided into four groups according to their age and vaccination route. Groups A (n=3) and B (n=3) consisted of non-pregnant lactating female camels, vaccinated through subcutaneou...
متن کاملResponse of the vaccine strain of Brucella melitensis Rev I to erythritol.
The vaccine strain of Brucella mnelitensis designated as Rev I (M. Herzberg and S. S. 'Elberg, J. Bacteriol. 66:585, 1953; 69:432, 1955) and used in the protection of goats and sheep against brucellosis is characterized by slow colony development (4 to 5 days) on various solid media, increased sensitivity to penicillin (5 to 10 units), and increased resistance to streptomycin (5 ,ug) as contras...
متن کاملCharacterization of heat, oxidative, and acid stress responses in Brucella melitensis.
Brucella melitensis is a facultative intracellular pathogen which is able to survive and replicate within phagocytic cells. Therefore, it has to adapt to a range of different hostile environments. In order to understand the mechanisms of intracellular survival employed by virulent B. melitensis 16M, an initial approach consisting of analysis of the differences in patterns of protein synthesis i...
متن کاملGenotoxicity of Dioxin and its Effect on the Immune Response of Goats Vaccinated with Brucella Melitensis Vaccine
The few cytogenetic studies performed in both humans and animals exposed in vivo or in vitro to dioxin reported conflicting data with or without chromosome damage. Therefore the aim of this work was to fulfill the genotoxicity of dioxin and its effect on immune response of sheep vaccinated with Brucella melitensis Rev.1 vaccine. A total number of twenty female goats were divided into four group...
متن کاملBiphasic Response to Luteolin in MG-63 Osteoblast-Like Cells under High Glucose‑Induced Oxidative Stress
Background: Clinical evidence indicates the diabetes-induced impairment of osteogenesis caused by a decrease in osteoblast activity. Flavonoids can increase the differentiation and mineralization of osteoblasts in a high-glucose state. However, some flavonoids such as luteolin may have the potential to induce cytotoxicity in osteoblast-like cells. This study was performed to investigate whether...
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ژورنال
عنوان ژورنال: Indian Journal of Animal Research
سال: 2018
ISSN: 0976-0555,0367-6722
DOI: 10.18805/ijar.b-3548